PET Radiopharmaceutical Development and Translation
for CNS imaging
- endocannabinoid system: fatty acid amide hydrolase (FAAH), monoacylglycerol lipase (MAGL) etc
- metabotropic and ionotropic glutamate system: mGluR2, AMPA, NMDA
- kinase targets: GSK3, ALK, RIPK, LRRK2, PI3K
- cholesterol homeostasis in the brain
- cerebellum function imaging
for cancer imaging
- PTK7 targeted aptamer imaging
- MHC class II immune imaging
- kinase based imaging: ALK, GSK3, PI3K
for cardiovascular imaging
- phosphodiesterases
- apelin system
for liver and IBD imaging
- integrin
- endocannabinoid system (PET drug repurposing)
- ATX
- S1P1 (PET drug repurposing)
Precision Radiochemistry
- novel radiochemical methods using 11C and 18F
- bioconjugation reaction with biological molecules, including aptamer, peptide and protein etc
