Tobias L. Lenz
"Although one could argue that MHC genes were created by God to frustrate transplant surgeons, most immunologists [and evolutionary biologists] find such an argument somewhat unsatisfactory."
J. Klein 1986
My research focuses on the evolution of genetic diversity in the human major histocompatibility complex (MHC) and the evolutionary significance of individual MHC diversity. I am interested in the mechanisms that create genetic diversity in the MHC region as well as the selective constraints that shape and maintain the exceptional genetic diversity at MHC and particularly at Human Leukocyte Antigen (HLA) loci.
In mid 2014 I have moved to the Max Planck Institute for Evolutionary Biology in Germany to start my own group in Evolutionary Immunogenomics (website).