Publications

2000
J. Xu, W.M. Purcell, and D.E. Ray. 2000. “Age difference in the metabolism of p-bromophenylacetylurea in the rat: An implication for age susceptibility to its neurotoxicity.” NeuroToxicology, 21, 3, Pp. 289-293.
K. Lakhani, N. Constantinovici, W.M. Purcell, R. Fernando, and P. Hardiman. 2000. “Internal carotid artery haemodynamics in women with polycystic ovaries.” Clinical Science (London), 98, 6, Pp. 661-665.
K. Lakhani, N. Constantinovici, W.M. Purcell, R. Fernando, and P. Hardiman. 2000. “Internal carotid-artery response to 5% carbon dioxide in women with polycystic ovaries.” Lancet, 356, 9236, Pp. 1166-1167.
W.M. Purcell and J. Xu. 2000. “· Spheroids 9702335.2, 9709899.0, PCT/GB98/00343 [WO 98/35021]· CNS Drugs 9702310.5, PCT/GB98/0035· Preparation of Spheroids PCT/GB01/05445UK Patent Application No. 0029847.1 filed on 7 December 2000PCT Patent Application No. PCT/GB01/05.” United Kingdom.
J. Xu, W.M. Purcell, and D.E. Ray. 2000. “Toxicokinetics and metabolism p-bromophenylacetylurea in the rat.” Xenobiotica; the fate of foreign compounds in biological systems, 30, 3, Pp. 307-315.
1999
J. Xu, J.H. Lamb, R. Jukes, W.M. Purcell, and D.E. Ray. 1999. “Application of the high-performance liquid chromatographic method for separation, purification and characterisation of p-bromophenylacetylurea and its metabolites.” Journal of Chromatography B: Biomedical Sciences and Applications, 732, 2, Pp. 349-356.
C.K. Atterwill, P. Goldfarb, and W.M. Purcell. 1999. APPROACHES TO HIGH THROUGHPUT TOXICITY SCREENING.. Taylor & Francis.
Stephan S, Purcell WM, and Chander CL. 1999. “Colony stimulating factors regulate nitric oxide and prostaglandin E2 production in rat cartilage chondrocytes.” International Journal of Tissue Reactions, 21, 4, Pp. 25-31.
S. Stephan, W.M. Purcell, and C.L. Chander. 1999. “Granulocyte-colony stimulating factor decreases glycosaminoglycan concentration and increases nitric oxide production in rat articular cartilage.” Inflammation Research, 48, S2, Pp. 126-127.
J. Xu, T. Lister, W.M. Purcell, and D.E. Ray. 1999. “Neurotoxic potentiation is related to a metabolic interaction between p-bromophenylacetylurea and phenylmethanesulfonyl fluoride.” Toxicology and Applied Pharmacology, 157, 3, Pp. 222-226.
A. Hutchings, W.M. Purcell, and M.R. Benfield. 1999. “Peripheral blood antigen-presenting cells from African-Americans exhibit increased CD80 and CD86 expression.” Clinical and Experimental Immunology, 118, 2, Pp. 247-252.
J. Xu, C.C. Nolan, T. Lister, W.M. Purcell, and D.E. Ray. 1999. “Pharmacokinetic factors and concentration-time threshold in m-dinitrobenzene-induced neurotoxicity.” Toxicology and Applied Pharmacology, 161, 3, Pp. 267-273.
A. C. Brooks, C.J. Whelan, and W.M. Purcell. 1999. “Reactive oxygen species generation and histamine release by activated mast cells: modulation by nitric oxide synthase inhibition.” British Journal of Pharmacology, 128, 3, Pp. 585-590.
1998
C.E. Teunissen, S.T. Kingston, D.C. Morse, W.M. Purcell, and C.K. Atterwill. 1998. “Application of rat and chick whole brain spheroids to polychlorinated biphenyl (PCB) neurotoxicity testing.” In Volatile Organic Compounds in the Environment, Risk Assessment and Neurotoxicity, 3: Pp. 263-272. Le Collane della Fondazione Salvatore Maugeri, PI-ME Press, Pavia.
K.P. Lakhani, M.S. Marsh, W.M. Purcell, and P. Hardiman. 1998. “Uterine artery blood flow parameters in women with dysfunctional uterine bleeding and uterine fibroids: the effects of tranexamic acid.” Ultrasound in Obstetrics & Gynecology, 11, 4, Pp. 283-285.
1996
C.K. Atterwill and W.M. Purcell. 1996. “BRAIN SPHEROID AND OTHER ORGANOTYPIC CULTURE SYSTEMS IN IN VITRO NEUROTOXICOLOGY.” In NEUROTOXICOLOGY IN VITRO, Chapter 9: Pp. 213-237. Taylor & Francis.
W.M. Purcell, C. Westgate, and C.K. Atterwill. 1996. “Rat brain mast cells: An in vitro paradigm for assessing the toxic effects of neurotropic therapeutics.” NeuroToxicology, 17, 3-4, Pp. 845-850.
W.M. Purcell, K.M. Doyle, C. Westgate, and C.K. Atterwill. 1996. “Characterisation of a functional polyamine site on rat mast cells: association with a NMDA receptor macrocomplex.” Journal of Neuroimmunology, 65, 1, Pp. 49-53.
1995
W.M. Purcell and C.K. Atterwill. 1995. “Mast cells in neuroimmune function: neurotoxicological and neuropharmacological perspectives.” Neurochemical Research, 20, 5, Pp. 521-532.
1994
W.M. Purcell, K.M. Doyle, L. Bagga, and M. Derks. 1994. “Histamine release from mast cells by polyamines: an NMDA receptor-mediated event?” Biochemical Society Transactions, 22, 4, Pp. 398S.

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