Principal Investigator

Wei TaoWei Tao, Ph.D.
Farokhzad Family Distinguished Chair for Innovation (#1), Omid C. Farokhzad Assistant Professor
(Endowed Chair)
Principal Investigator, Center for Nanomedicine
Faculty Member, Department of Anesthesiology, Perioperative, and Pain Medicine 
Faculty Member, Gillian Reny Stepping Strong Center for Trauma Innovation 
Brigham and Women’s Hospital, Harvard Medical School
Email: wtao@bwh.harvard.edu 
60 Fenwood Road, Boston, MA 02115
Phone: 857-320-9992; Fax: 857-307-2337

Bio: Prof. Wei Tao is the Farokhzad Family Distinguished Chair for Innovation and Principal Investigator in the Center for Nanomedicine, Faculty Member in the Department of Anesthesiology, Perioperative, and Pain Medicine, and Faculty Member in the Gillian Reny Stepping Strong Center for Trauma Innovation at Brigham and Women’s Hospital (BWH), Harvard Medical School (HMS). He is also the first Chaired Professor as an assistant professor in the history of his institution. He has received multiple awards/grants including the U.S. METAvivor Early Career Investigator Award, HMS/BWH Anaesthesia Department Basic Scientist Grant, Khoury Innovation Award, Center for Nanomedicine Research Fund, Stepping Strong Breakthrough Innovator Award, American Heart Association (AHA) Collaborative Sciences Award, MIT Technology Review Top Chinese Innovators Under 35 (TR35), Clarivate’s Global Highly Cited Researcher (since 2021), World's Top 2% Scientist (from Mendeley Data, Elsevier; since 2019), Chemical Society Reviews Emerging Investigator, Advanced Materials Rising Star, Materials Today Rising Star Award, Angewandte Chemie Most Outstanding Referees Award, Materials Horizons Top 10 Outstanding Reviewers Award, Nanoscale Emerging Investigator, Precision Nanomedicine Rising Talents Award, etc. He also serves on numerous editorial boards including as Associate Editor of Journal of Nanobiotechnology (Springer Nature & BMC) and Exploration (Wiley); Guest Editor of eLife, etc.; Editorial Board Member of Bioactive Materials (Elsevier, KeAi), Nano-Micro Letters (Springer Nature), etc.; and Advisory Board Member of Matter (Cell Press).

• See Prof. Tao's interview (together with Prof. Robert Langer/MIT, Prof. Samir Mitragotri/Harvard, Dr. Nicholas Warne/Pfizer, Dr. Steffen Panzner/BioNTech, etc.) in Nature Medicine (pdf)

Research Overview: Prof. Tao's primary research interest is in the design and synthesis of functional biomaterials, revealing nano-bio interactions (mechanism studies), and exploring their different biomedical applications including RNA therapeutics, cancer theranostics, wound healing, cardiovascular disease, bone regeneration, diabetes treatment and so on. His research thrusts include fundamental materials innovation as well as their various applications in translational medicine (not limited to the areas mentioned above). He is willing to have potential collaborators to expand the application fields of these materials.

 

List of Research Areas: Biomaterials, RNA Therapeutics, Drug Delivery, Biomedical Engineering, Nanomedicine.

 

Awards & Honors

Advanced Materials Rising Star

• Angewandte Chemie Most Outstanding Referees (Top 10% Reviewers) in 2021

• Clarivate’s Global Highly Cited Researcher (Cross-Field), Web of Science (Selected continuously every year since 2021)

Materials Today Rising Star Award
• World's Top 2% Scientists, published in Mendeley Data from Elsevier (Selected continuously every year since 2019)
Chemical Society Reviews Emerging Investigator Award, Royal Society of Chemistry
• Rising Talents Award, Precision Nanomedicine (PRNANO)
• Microsoft Academic Top 5 Trending Authors in Nanotechnology (2016-2020), and Top Authors in Nanomedicine
Nanoscale Emerging Investigator Award, Royal Society of Chemistry
• MIT Technology Review Top Chinese Innovators Under 35 (2020 TR35)
• Harvard & Brigham Khoury Innovation Award (PI)

• Harvard/Brigham Assistant Professor Department Start-Up Package (PI)

• Harvard & Brigham Stepping Strong Breakthrough Innovator Award (PI)
• Top 10 Outstanding Reviewers in 2019, Materials Horizons
• Featured Investigator at Harvard & Brigham Anaesthesia Department
• Harvard & Brigham Center for Nanomedicine Research Fund (PI)
• American Heart Association (AHA) Collaborative Sciences Award (PI)
• Harvard & Brigham Anaesthesia Department Basic Science Seed Grant (PI)
• US METAvivor Early Career Investigator Award (PI)
• Outstanding Reviewer Award, Acta Biomaterialia

 

Recent Publications

• Huang X, ..., Tao W*. The landscape of mRNA nanomedicine. Nature Medicine 2022, in press.

• Huang X, ..., Tao W*. Nanotechnology-based strategies against SARS-CoV-2 variants. Nature Nanotechnology 2022, DOI: 10.1038/s41565-022-01174-5.

Kong N, …, Tao W*. Intravesical delivery of KDM6A-mRNA via mucoadhesive nanoparticles inhibits the metastasis of bladder cancer. PNAS 2022, 119(7): e2112696119.

• Huang X, …, Tao W*. Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages. Nature Protocols 2022, 17(3): 748–780.

• Chen W, …, Tao W*. Macrophage-targeted nanomedicine for diagnosis and treatment of atherosclerosis. Nature Reviews Cardiology 2022, 19(4): 228–249.

• Ji X, …, Tao W*. Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics. Nature Communications 2021, 12: 1124.

• Ouyang J, …, Tao W*In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment. PNAS 2020, 117(46): 28667-28677.

• Tang Z, …, Tao W*. A materials science perspective on tackling COVID-19. Nature Reviews Materials 2020, 5(11): 847-860.