Cover Features


(“#” denotes equal contribution; “*” denotes corresponding author)
In Progress
45. Zheng M, Tao W, Zou Y, Farokhzad OC, Shi B. Trends in Biotechnology 2017, (Invited review).
44. Islam AM, Xu Y, Tao W, Lim M, Zope H, Cao W, Mahmoudi M, Langer R, Kantoff P, Shi J, Zetter B, Farokhzad OC. Nature Biomedical Engineering 2017,  (Under 2nd Revision)
43. Ding L, Wang Y, Zhu X, Ling X, Chen H, Nan W, Barrett A, Guo Z, Tao W*, Wu J*, Shi X*. Nano Letters 2017, (Under Revision)
42.Zhu X#, Ji X#, Mahmoudi M, Xu X, Ding L, Tao W*, Cai T, Barrett A, Bharwani Z, Chen Y, Chen H, Farokhzad OC*. ACS Nano, (Under Revision)
41.Tao W, Ji X, Zhu X, Xu X, Saw PE, Zhang J, Yu M, Mahmoudi M, Ding J, Zeng X, Zhang X, Barrett, Zhang H, Farokhzad OC*. Nano Letters. (To be submitted soon)

40. Wang J#, Tao W#, Chen X*, Farokhzad OC*, Liu G*. Emerging advances in nanotheranostics with intelligent bioresponsive systems. Theranostics. 2017; (Accept).


39. Nie J, Cheng W, Peng Y, Liu G, Chen Y, Wang X, Liang C, Tao W, Wei Y, Zeng X*, Mei L*. Co-delivery of docetaxel and bortezomib based on a targeting nanoplatform for enhancing cancer chemotherapy effects. Drug Delivery 2017 Nov; 24(1):1124-1138. PMID: 28789585.

Drug Delivery

38. Tao W*, Liu G, Zeng X, Mei L. Multi-functionalized polymeric nanoparticles realized enhanced drug loading efficiency, extended circulation time, and significant in vivo tumor targeting effect. Journal of Controlled Release 2017; 259:e133-134.

Journal of Controlled Release

37. Behzadi S, Serpooshan V, Tao W, Hamaly MA, Alkawareek MY, Dreaden EC, Brown D, Alkilany AM*, Farokhzad OC*, Mahmoudi M*. Cellular uptake of nanoparticles: journey inside the cell. Chemical Society Reviews 2017 Jul 17; 46(14):4218-4244. PMID: 28585944.(Cover Feature Paper)

Chemical Society Reviews

36. Shi B*, Zheng M, Tao W, Chung R, Jin D, Ghaffari D, Farokhzad OC*. Challenges in DNA Delivery and Recent Advances in Multifunctional Polymeric DNA Delivery Systems. Biomacromolecules 2017 Jul 14. PMID: 28661127.


35. Xu X#, Saw PE#, Tao W, Li Y, Ji X, Bhasin S, Liu Y, Ayyash D, Rasmussen J, Huo M, Shi J*, Farokhzad OC*. ROS-Responsive Polyprodrug Nanoparticles for Triggered Drug Delivery and Effective Cancer Therapy. Advanced Materials 2017 Jul 06. PMID: 28681981.

Advanced Materials

34. Xu X, Saw PE, Tao W, Li Y, Ji X, Yu M, Mahmoudi M, Rasmussen J, Ayyash D, Zhou Y, Farokhzad OC*, Shi J*. Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy. Nano Letters 2017 Jul 12; 17(7):4427-4435. PMID: 28636389.

Nano Letters

33. Tao W, Ji X, Xu X, Islam MA, Li Z, Chen S, Saw PE, Zhang H, Bharwani Z, Guo Z, Shi J*, Farokhzad OC*. Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy. Angewandte Chemie International Edition 2017 Jun 22. PMID: 28640986. (Cover Feature Paper; Highlighted by Advanced Science News)


32. Cheng W, Liang C, Xu L, Liu G, Gao N, Tao W, Luo L, Zuo Y, Wang X, Zhang X, Zeng X*, Mei L*. TPGS-Functionalized Polydopamine-Modified Mesoporous Silica as Drug Nanocarriers for Enhanced Lung Cancer Chemotherapy against Multidrug Resistance. Small 2017 Jun 08. PMID: 28594473.(Cover Feature Paper)


31. Zhu X#, Tao W#, Liu D, Wu J, Guo Z, Ji X, Bharwani Z, Zhao L, Chen X, Zhao X, Farokhazd O*, Shi J*. Surface De-PEGylation Controls Nanoparticle-Mediated siRNA Delivery In Vitro and In Vivo. Theranostics 2017; 7(7):1990-2002.


30. Liu G, Tsai HI, Zeng X, Zuo Y, Tao W, Han J, Mei L*. Phosphorylcholine-based stealthy nanocapsules enabling tumor microenvironment-responsive doxorubicin release for tumor suppression. Theranostics 2017; 7(5):1192-1203. PMID: 28435458. (Cover Feature Paper)


29. Xu X#, Wu J#, Liu Y, Saw PE, Tao W, Yu M, Zope H, Si M, Victorious A, Rasmussen J, Ayyash D, Farokhzad OC*, Shi J*. Multifunctional Envelope-Type siRNA Delivery Nanoparticle Platform for Prostate Cancer Therapy. ACS Nano 2017 Mar 28; 11(3):2618-2627. PMID: 28240870.

 ACS Nano

28. Zhang J, Chang D, Yang Y, Zhang X, Tao W, Jiang L, Liang X, Tsai H, Huang L*, Mei L*. Systematic investigation on the intracellular trafficking network of polymeric nanoparticles. Nanoscale 2017 Mar 02; 9(9):3269-3282. PMID: 28225130.


27. Zeng X#, Liu G#, Tao W#, Ma Y, Zhang X, He F, Pan J*, Mei L*, Pan G*. A Drug-Self-Gated Mesoporous Antitumor Nanoplatform Based on pH-Sensitive Dynamic Covalent Bond. Advanced Functional Materials 2017; 1605985.(Cover Feature Paper; Most-Accessed Paper Top 1; Highlighted by Materials Views, Tsinghua University News, etc.)


26. Sun Z, Zhao Y, Li Z, Cui H, Zhou Y, Li W, Tao W, Zhang H*, Wang H, Chu PK*, Yu XF*. TiL4 -Coordinated Black Phosphorus Quantum Dots as an Efficient Contrast Agent for In Vivo Photoacoustic Imaging of Cancer. Small 2017 Mar; 13(11). PMID: 28060458. (Cover Feature Paper)


25. Liu G, Gao H, Zuo Y, Zeng X, Tao W, Tsai HI, Mei L*. DACHPt-Loaded Unimolecular Micelles Based on Hydrophilic Dendritic Block Copolymers for Enhanced Therapy of Lung Cancer. ACS Applied Materials & Interfaces 2017 01 11; 9(1):112-119. PMID: 27966356.


24. Zhang X, Liang X, Gu J, Chang D, Zhang J, Chen Z, Ye Y, Wang C, Tao W, Zeng X, Liu G, Zhang Y*, Mei L*, Gu Z*. Investigation and intervention of autophagy to guide cancer treatment with nanogels. Nanoscale 2017 Jan 07; 9(1):150-163. PMID: 27910983.


23. Tao W, Zhu X, Yu X, Zeng X, Xiao Q, Zhang X, Ji X, Wang X, Shi J*, Zhang H*, Mei L*. Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics. Advanced Materials 2017 Jan; 29(1). PMID: 27797119. (Cover Feature Paper; Highlighted by Materials Views, Science and Technology Daily, Chinese Academy of Sciences, China Science Communication, Materials China, NetEase Tech, JRJC, China Finance News, China's Education Ministry, X-MOL, etc.)

 Advanced Materials

22. Shan W, Zhu X, Tao W, Cui Y, Liu M, Wu L, Li L, Zheng Y, Huang Y*. Enhanced Oral Delivery of Protein Drugs Using Zwitterion-Functionalized Nanoparticles to Overcome both the Diffusion and Absorption Barriers. ACS Applied Materials & Interfaces 2016 Sep 28; 8(38):25444-53. PMID: 27588330.

ACS Applied Materials & Interfaces

21. Zhang J, Zhang X, Liu G, Chang D, Liang X, Zhu X, Tao W, Mei L*. Intracellular Trafficking Network of Protein Nanocapsules: Endocytosis, Exocytosis and Autophagy. Theranostics 2016; 6(12):2099-2113. PMID: 27698943.


20. Xu G#, Yu X#, Zhang J#, Sheng Y, Liu G, Tao W*, Mei L. Robust aptamer-polydopamine-functionalized M-PLGA-TPGS nanoparticles for targeted delivery of docetaxel and enhanced cervical cancer therapy. International Journal of Nanomedicine 2016; 11:2953-65. PMID: 27382282; PMCID: PMC4922762.

International Journal of Nanomedicine

19. Zhang X, Zhang H, Liang X, Zhang J, Tao W, Zhu X, Chang D, Zeng X, Liu G, Mei L*. Iron Oxide Nanoparticles Induce Autophagosome Accumulation through Multiple Mechanisms: Lysosome Impairment, Mitochondrial Damage, and ER Stress. Molecular Pharmaceutics 2016 Jul 05; 13(7):2578-87. PMID: 27287467.

 Molecular Pharmaceutics

18. Tao W, Zeng X, Wu J, Zhu X, Yu X, Zhang X, Zhang J, Liu G, Mei L*. Polydopamine-Based Surface Modification of Novel Nanoparticle-Aptamer Bioconjugates for In Vivo Breast Cancer Targeting and Enhanced Therapeutic Effects. Theranostics 2016; 6(4):470-84. PMID: 26941841; PMCID: PMC4775858. (Cover Feature Paper)


17. Zhu X#, Wu J#, Shan W, Tao W, Zhao L, Lim JM, D'Ortenzio M, Karnik R, Huang Y*, Shi J*, Farokhzad OC*. Polymeric Nanoparticles Amenable to Simultaneous Installation of Exterior Targeting and Interior Therapeutic Proteins. Angewandte Chemie International Edition 2016 Mar 01; 55(10):3309-12. PMID: 26846161; PMCID: PMC4835185.(Featured as Hot Paper)

Angewandte Chemie International Edition

16. Zhu D, Tao W, Zhang H, Liu G, Wang T, Zhang L, Zeng X*, Mei L*. Docetaxel (DTX)-loaded polydopamine-modified TPGS-PLA nanoparticles as a targeted drug delivery system for the treatment of liver cancer. Acta Biomaterialia 2016 Jan; 30:144-54. PMID: 26602819.

Acta Biomaterialia

15. Chang D, Gao Y, Wang L, Liu G, Chen Y, Wang T, Tao W, Mei L, Huang L*, Zeng X*. Polydopamine-based surface modification of mesoporous silica nanoparticles as pH-sensitive drug delivery vehicles for cancer therapy. Journal of Colloid and Interface Science 2016 Feb 01; 463:279-87. PMID: 26550786.

 Journal of Colloid and Interface Science

14. Zeng X, Tao W, Mei L, Feng SS*. Docetaxel-loaded nanoparticles of dendrimer-like amphiphilic copolymer for cancer therapy. Journal of Controlled Release 2015 Sep 10; 213:e119. PMID: 27005059.

 Journal of Controlled Release

13. Wu Y, Wang Z, Liu G, Zeng X, Wang X, Gao Y, Jiang L, Shi X, Tao W, Huang L*, Mei L*. Novel Simvastatin-Loaded Nanoparticles Based on Cholic Acid-Core Star-Shaped PLGA for Breast Cancer Treatment. Journal of Biomedical Nanotechnology 2015 Jul; 11(7):1247-60. PMID: 26307847.

Journal of Biomedical Nanotechnology

12. Zhu X*, Xu Y*, Solis LM, Tao W, Wang L, Behrens C, Xu X, Zhao L, Liu D, Wu J, Zhang N, Wistuba II, Farokhzad OC, Zetter BR, Shi J*. Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment. Proceedings of the National Academy of Sciences of the United States of America 2015 Jun 23; 112(25):7779-84. PMID: 26056316; PMCID: PMC4485147.


11. Zhang J#, Tao W#, Chen Y#, Chang D, Wang T, Zhang X, Mei L, Zeng X*, Huang L*. Doxorubicin-loaded star-shaped copolymer PLGA-vitamin E TPGS nanoparticles for lung cancer therapy. Journal of Materials Science: Materials in Medicine 2015 Apr; 26(4):165. PMID: 25791459.

Journal of Materials Science: Materials in Medicine

10. Tao W, Zhang J, Zeng X, Liu D, Liu G, Zhu X, Liu Y, Yu Q, Huang L*, Mei L*. Blended nanoparticle system based on miscible structurally similar polymers: a safe, simple, targeted, and surprisingly high efficiency vehicle for cancer therapy. Advanced Healthcare Materials 2015 Jun 03; 4(8):1203-14. PMID: 25800699.(Cover Feature Paper)

Advanced Healthcare Materials

9. Wang T, Zhu D, Liu G, Tao W, Cao W, Zhang L, Wang L, Chen H, Mei L, Huang L*, Zeng X*. DTX-loaded star-shaped TAPP-PLA-b-TPGS nanoparticles for cancer chemical and photodynamic combination therapy. RSC Advances 2015; 5(62):50617-50627.

RSC Advances

8. Zeng X#, Tao W#, Wang Z, Zhang X, Zhu H, Wu Y, Gao Y, Liu K, Jiang Y, Huang L, Mei L*, Feng SS*. Docetaxel-Loaded Nanoparticles of Dendritic Amphiphilic Block Copolymer H40-PLA-b-TPGS for Cancer Treatment. Particle & Particle Systems Characterization. 2015; 32(1):112-122.

Particle & Particle Systems Characterization


7. Zhang X, Yang Y, Liang X, Zeng X, Liu Z, Tao W, Xiao X, Chen H, Huang L, Mei L*. Enhancing therapeutic effects of docetaxel-loaded dendritic copolymer nanoparticles by co-treatment with autophagy inhibitor on breast cancer. Theranostics. 2014; 4(11):1085-95. PMID: 25285162; PMCID: PMC4173759.


6. Tao W, Zeng X, Zhang J, Zhu H, Chang D, Zhang X, Gao Y, Tang J, Huang L*, Mei L*. Synthesis of cholic acid-core poly(e-caprolactoneran-lactide)-b-poly(ethylene glycol) 1000 random copolymer as a chemotherapeutic nanocarrier for liver cancer treatment. Biomaterials Science 2014; 2(9):1262-1274.

Biomaterials Science

5. Zhang X, Dong Y, Zeng X, Liang X, Li X, Tao W, Chen H, Jiang Y, Mei L*, Feng SS*. The effect of autophagy inhibitors on drug delivery using biodegradable polymer nanoparticles in cancer treatment. Biomaterials 2014 Feb; 35(6):1932-43. PMID: 24315578.(ISI Web of Knowledge: Highly Cited Papers)


2013 and before
4. Tao W, Zeng X, Liu T, Wang Z, Xiong Q, Ouyang C, Huang L*, Mei L*. Docetaxel-loaded nanoparticles based on star-shaped mannitol-core PLGA-TPGS diblock copolymer for breast cancer therapy. Acta Biomaterialia 2013 Nov; 9(11):8910-20. PMID: 23816645.(ISI Web of Knowledge: Highly Cited Papers)

Acta Biomaterialia

3. Zeng X#, Tao W#, Mei L*, Huang L, Tan C, Feng SS*. Cholic acid-functionalized nanoparticles of star-shaped PLGA-vitamin E TPGS copolymer for docetaxel delivery to cervical cancer. Biomaterials 2013 Aug; 34(25):6058-67. (ISI Web of Knowledge: Highly Cited Papers)


2. Zeng X, Chen H, Zheng Y, Tao W, Fan Y, Huang L*, Mei L*. Enhanced adsorption of puerarin onto a novel hydrophilic and polar modified post-crosslinked resin from aqueous solution. Journal of Colloid and Interface Science 2012 Nov 01; 385(1):166-73. PMID: 22878002.

Journal of Colloid and Interface Science

Book Chapter
1. Tao W, Mei L. Nanobiomaterials: Classification, Fabrication and Biomedical Applications. Wiley-VCH Verlag GmbH & Co. KGaA. 2017. (“Nanobiomaterials for Cancer Therapy” of Part 4)