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Selected First/Corresponding Author Publications (View All Publications)

Selected Publications in Nature/Science/Cell Press/PNAS Group Journals: 25+


59. Yi Y, Yu M, Feng C, Hao H, Zeng W, Lin C, Chen H, Lv F, Zhu D, Ji X, Mei L, Wu M, Tao W*. Transforming "Cold" Tumors into "Hot" Ones via Tumor Microenvironment-Responsive siRNA Micelleplexes for Enhanced Immunotherapy. Matter (Cell Press) 2022, in press.

58. Ouyang J, Xie A, Zhou J, Liu R, Wang L, Liu H, Kong N, Tao W*. Minimally invasive nanomedicine: nanotechnology in photo-/ultrasound-/radiation-/magnetism-mediated therapy and imaging. Chemical Society Reviews 2022, DOI: 10.1039/d1cs01148k. (Invited ArticleEmerging Investigator Award Collection)

57. Xiao Y, Tang Z, Huang X, Chen W, Zhou J, Liu H, Liu C, Kong N, Tao W*. Emerging mRNA technologies: Delivery strategies and biomedical applications. Chemical Society Reviews 2022, 51(10): 3828-3845(Front Cover Paper)

56. Kong N, Zhang R, Wu G, Sui X, Wang J, Kim NY, Blake S, De D, Xie T, Cao Y, Tao W*. Intravesical Delivery of KDM6A-mRNA via Mucoadhesive Nanoparticles Inhibits the Metastasis of Bladder Cancer. Proceedings of the National Academy of Sciences USA (PNAS) 2022, 119(7): e2112696119. (Front Cover Paper)

55. Tao W*, Peppas NA. Robotic pills for gastrointestinal-tract-targeted oral mRNA delivery. Matter (Cell Press) 2022, 5(3): 775-777. (Invited Article)

54. Zhang Z, Zhou J, Liu C, Zhang J, Shibata Y, Kong N, Corbo C, Harris MB, Tao W*. Emerging Biomimetic Nanotechnology in Orthopedic Diseases: Progress, Challenges, and Opportunities. Trends in Chemistry (Cell Press) 2022, 4(5): 420-436.

53. Chen W, Tao W*. Precise Control of the Structure of Synthetic Hydrogel Networks for Precision Medicine Applications. Matter (Cell Press) 2022, 5(1): 18-19. (Invited Article)

52. Huang X, Liu C, Kong N, Xiao Y, Yurdagul A, Tabas I, Tao W*. Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages. Nature Protocols 2022, 17(3): 748–780(Featured article by Nature Protocols)

51. Chen W, Schilperoort M, Cao Y, Shi J, Tabas I, Tao W*. Macrophage-Targeted Nanomedicine for Diagnosis and Treatment of Atherosclerosis. Nature Reviews Cardiology 2022, 19(4): 228–249. (Cover Featured; Highlighted in the "Mechanisms of atherosclerosis" Series of articles from Nature Reviews Cardiology)

50. Zhao M, Mi D, Ferdows BE, Li Y, Wang R, Li J, Patel D, Kong N, Shi S, Tao W*. State-of-the-art nanotechnologies for the detection, recovery, analysis and elimination of liquid biopsy components in cancer. Nano Today 2022, 42: 101361.

49. Ouyang J, Rao S, Liu R, Wang L, Chen W, Tao W*, Kong N. 2D Materials-based Nanomedicine: From Discovery to Applications. Advanced Drug Delivery Reviews 2022, 185: 114268. (Invited Article)

48. Zhang D, Zhong D, Ouyang J, He J, Qi Y, Chen W, Zhang X, Tao W*, Zhou M. Microalgae-based oral microcarriers for gut microbiota homeostasis and intestinal protection in cancer radiotherapy. Nature Communications 2022, 13: 1413.

47. Jangili P, Kong N, Kim JH, Zhou J, Liu H, Zhang X, Tao W*, Kim JS. DNA-Damage-Response-Targeting Mitochondria-Activated Multifunctional Prodrug Strategy for Self-defensive Tumor Therapy. Angewandte Chemie International Edition 2022, 61(16): e202117075. (Angew. Chem. VIP and Front Cover Paper)


46. Huang X, Wu G, Liu C, Hua X, Tang Z, Xiao Y, Chen W, Zhou J, Kong N, Huang P, Shi J, Tao W*. Intercalation-driven Formation of siRNA Nanogels for Cancer Therapy. Nano Letters 2021, 21(22): 9706-9714.

45. Zhong D, Zhang D, Chen W, He J, Ren C, Zhang X, Kong N, Tao W*, Zhou M. Orally Deliverable Strategy Based on Microalgal Biomass for Intestinal Diseases Treatment. Science Advances 2021, 7(48): eabi9265(Front Cover Paper)

44. Zhao H, Xu J, Feng C, Ren J, Bao L, Zhao Y, Tao W*, Zhao Y, Yang X. Tailoring Aggregation Extent of Photosensitizer to Boost Phototherapy Potency for Eliciting Systemic Antitumor Immunity. Advanced Materials 2022, 34(8): e2106390.

43. Singh N, Son S, An J, Kim I, Choi M, Kong N, Tao W*, Kim JS. Nanoscale porous organic polymers for drug delivery and advanced cancer theranostics. Chemical Society Reviews 2021, 50(23): 12883-12896.

42. Zhou J, Zhang Z, Joseph J, Zhang X, Ferdows BE, Patel DN, Chen W, Banfi G, Molinaro R, Cosco D, Kong N, Joshi N, Farokhzad OC, Corbo C, Tao W*. Biomaterials and Nanomedicine for Bone Regeneration: Progress and Future Prospects. Exploration 2021, 1(2): 20210011. (Front Cover Paper) (Invited Article)

41. Li S, Wang L, Gu Y, Lin L, Zhang M, Jin M, Mao C, Zhou J, Zhang W, Huang X, Corbo C, Tao W*, Lu E, Liu J. Biomimetic immunomodulation by crosstalk with nanoparticulate regulatory T cells. Matter (Cell Press) 2021, 4(11): 3621-3645.

40. Tao W*, Farokhzad OC. Theranostic Nanomedicine in the NIR-II Window: Classification, Fabrication, and Biomedical Applications. Chemical Reviews 2022, 122(6): 5405-5407(Invited Article)

39. Xiao Y, Tang Z, Huang X, Joseph J, Chen W, Liu C, Zhou J, Kong N, Joshi N, Du J, Tao W*. Glucose-responsive oral insulin delivery platform for onetreatment-a-day in diabetes. Matter (Cell Press) 2021, 4(10): 3269–3285. Highlighted: Matter, 2021, 4(12): 3790-3791.

38. Kong N, Zhang H, Feng C, Liu C, Xiao Y, Zhang X, Mei L, Kim JS, Tao W*, Ji X. Arsenene-mediated multiple independently targeted reactive oxygen species burst for cancer therapy. Nature Communications 2021, 12: 4777Highlighted: Nature Portfolio | Bioengineering Community - “Multi-targeted reactive oxygen species burst for cancer therapy” (Web of Science Hot Paper | Highly Cited Paper)

37. Zhang X, Li L, Ouyang J, Zhang L, Xue J, Zhang H, Tao W*. Electroactive electrospun nanofibers for tissue engineering. Nano Today 2021, 39: 101196. (Web of Science Highly Cited Paper)

36. Zhang X, Koo S, Kim JH, Huang X, Kong N, Zhang L, Zhou J, Xue J, Harris MB, Tao W*, Kim JS. Nanoscale Materials-Based Platforms for the Treatment of Bone-Related Diseases. Matter (Cell Press) 2021, 4(9): 2727-2764.

35. Liu C, Sun S, Feng Q, Wu G, Wu Y, Kong N, Yu Z, Yao J, Zhang X, Chen W, Tang Z, Xiao Y, Huang X, Lv A, Yao C, Cheng H, Wu A, Xie T, Tao W*Arsenene Nanodots with Selective Killing Effects and their Low-Dose Combination with ß-Elemene for Cancer Therapy. Advanced Materials 2021, 33(37): 2102054. (Frontispiece Cover PaperWeb of Science Hot Paper | Highly Cited Paper)

34. Ouyang J, Feng C, Zhang X, Kong N, Tao W*. Black Phosphorus in Biomedical Applications: Evolutionary Journey from Monoelemental Materials to Composite Materials. Accounts of Materials Research 2021, 2(7): 489–500. (ACS Editors' Choice Featured; Front Cover Paper)

33. Farokhzad N, Tao W*. Materials Chemistry-Enabled Platforms in Detecting Sexually Transmitted Infections: Progress towards Point-of-Care Tests. Trends in Chemistry (Cell Press) 2021, 3(7): 589-602. (Invited Article

32. Zhang X, Duan X, Hu Y, Tang Z, Miao C, Tao W*, Wu J. One-step and facile synthesis of peptide-like poly(melphalan) nanodrug for cancer therapy. Nano Today 2021, 37:101098. (Web of Science Highly Cited Paper)

31. Ouyang J, Zhang L, Li L, Chen W, Tang Z, Ji X, Feng C, Tao N, Kong N, Chen T, Liu Y, Tao W*. Cryogenic Exfoliation of 2D Stanene Nanosheets for Cancer Theranostics. Nano-Micro Letters 2021, 13: 90. 

30. Ji X, Ge L, Liu C, Tang Z, Xiao Y, Chen W, Lei Z, Gao W, Blake S, De D, Shi B, Zeng X, Kong N, Zhang X, Tao W*. Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics. Nature Communications 2021, 12: 1124. Highlighted: Nature Portfolio | Bioengineering Community - “Nature-Derived 2-Dimensional Materials for Cancer Therapy and Sustainable Solutions” (Web of Science Hot Paper | Highly Cited Paper)

29. Liu C, Shin J, Son S, Choe Y, Farokhzad N, Tang Z, Xiao Y, Kong N, Xie T, Kim JS, Tao W*Pnictogens in Medicinal Chemistry: Evolution from Erstwhile Drugs to Emerging Layered Photonic Nanomedicine. Chemical Society Reviews 2021, 50(4): 2260-2279. (Web of Science Highly Cited Paper)

28. Chen W, Liu C, Ji X, Joseph J, Tang Z, Ouyang J, Xiao Y, Kong N, Joshi N, Farokhzad OC, Tao W*, Xie T. Stanene-Based Nanosheets for ß-Elemene Delivery and Ultrasound-Mediated Combination Cancer Therapy. Angewandte Chemie International Edition 2021, 60(13): 7155-7164. (Angew. Chem. VIP and Front Cover Paper; Web of Science Highly Cited Paper) 

27. Yang J, Zhang X, Liu C, Wang Z, Deng L, Feng C, Tao W*, Xu X, Cui W. Biologically Modified Nanoparticles as Theranostic Bionanomaterials. Progress in Materials Science 2021, 118: 100768. 

26. Tang Z, Zhang X, Shu Y, Guo M, Zhang H, Tao W*. Insights from nanotechnology in COVID-19 treatment. Nano Today 2021, 36:101019. (Most Downloaded Nano Today Articles - TOP 2Web of Science Highly Cited Paper

25. Liu Y, Wang J, Xiong Q, Hornburg D, Tao W*, Farokhzad OC. Nano-Bio Interactions in Cancer: from Therapeutics Delivery to Early Detection. Accounts of Chemical Research 2021, 54(2): 291–301. (Cover PaperWeb of Science Highly Cited Paper) (Invited Article


24. Zhang Z, Tang Z, Farokhzad N, Chen T, Tao W*Sensitive, Rapid, Low-cost and Multiplexed COVID-19 Monitoring by the Wireless Telemedicine Platform. Matter (Cell Press) 2020, 3(6): 1818-1820. (Invited Article)

23. Ouyang J, Ji X, Zhang X, Feng C, Tang Z, Kong N, Xie A, Wang J, Sui X, Deng L, Liu Y, Kim JS, Cao Y, Tao W*In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment. Proceedings of the National Academy of Sciences USA (PNAS) 2020, 117(46): 28667-28677. (Web of Science Highly Cited PaperHighlighted: Materials Research Society (MRS) Bulletin Materials News (MRS Bulletin 2021, 46(3): 199)

22. Tang Z, Kong N, Zhang X, Liu Y, Hu P, Mou S, Liljeström P, Shi J, Tan W, Kim JS, Cao Y, Langer R, Leong K, Farokhzad OC, Tao W*. A materials science perspective on tackling COVID-19. Nature Reviews Materials 2020, 5(11): 847-860. (Front Cover PaperWeb of Science Highly Cited PaperHighlighted: Nature Portfolio Bioengineering Community - “Tackling COVID-19 with materials science”

21. Huang W, He L, Ouyang J, Chen Q, Liu C, Tao W*, Chen T. Triangle-Shaped Tellurium Nanostars Potentiate Radiotherapy by Boosting Checkpoint Blockade Immunotherapy. Matter (Cell Press) 2020, 3(5): 1725-1753.

20. Ouyang J, Tang Z, Farokhzad N, Kong N, Kim NY, Feng C, Blake S, Xiao Y, Liu C, Xie T, Tao W*. Ultrasound Mediated Therapy: Recent Progress and Challenges in Nanoscience. Nano Today 2020, 35: 100949. 

19. Xiao Y, Tang Z, Wang J, Liu C, Kong N, Farokhzad OC, Tao W*Oral insulin delivery platforms: Strategies to address the biological barriers. Angewandte Chemie International Edition 2020, 59(45): 19787-19795. (Angew. Chem. VIP and Cover Paper) (Invited Article

18. Tao W, Yurdagul A, Kong N, Li W, Wang X, Doran A, Feng C, Wang J, Islam MA, Farokhzad OC, Tabas I, Shi J. siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice. Science Translational Medicine 2020, 12(553): eaay1063. (Front Cover PaperHighlighted: Nature Reviews Cardiology 2020, 17(10): 612; Matter (Cell Press) 2020, 3(3): 621-622

17. Hu K, Xie L, Zhang Y, Hanyu M, Yang Z, Nagatsu K, Suzuki H, Ouyang J, Ji X, Wei J, Xu H, Farokhzad OC, Liang SH, Wang L, Tao W*, Zhang MR. Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy. Nature Communications 2020, 11(1): 2778(Web of Science Highly Cited Paper

16. Feng C, Ouyang J, Tang Z, Kong N, Liu Y, Fu L, Ji X, Xie T, Farokhzad OC, Tao W*. Germanene-based Theranostic Materials for Surgical Adjuvant Treatment: Inhibiting Tumor Recurrence and Wound Infection. Matter (Cell Press) 2020, 3(1): 127-144. (Front Cover Paper; Web of Science Highly Cited PaperHighlighted: Matter (Cell Press), 2020, 3(1): 12-13

15. Kong N, Ji X, Wang J, Sun X, Chen G, Fan T, Liang W, Zhang H, Xie A, Farokhzad OC, Tao W*. ROS-Mediated Selective Killing Effect of Black Phosphorus: Mechanistic Understanding and Its Guidance for Safe Biomedical Applications. Nano Letters 2020, 20(5): 3943-3955. (Web of Science Highly Cited Paper

14. Tang Z, Kong N, Ouyang J, Feng C, Kim NY, Ji X, Wang C, Farokhzad OC, Zhang H, Tao W*. Phosphorus Science oriented Design and Synthesis of Multifunctional Nanomaterials for Biomedical Applications. Matter (Cell Press) 2020, 2(2): 297-322. (Web of Science Highly Cited Paper

13. Ji X, Kang Y, Fan T, Xiong Q, Zhang S, Tao W*, Zhang H. An antimonene/Cp* Rh (phen) Cl/black phosphorus hybrid nanosheet-based Z-scheme artificial photosynthesis for enhanced photo/bio-catalytic CO2 reduction. Journal of Materials Chemistry A 2020, 8(1): 323-333. 

Before 2019

12. Kong N#, Tao W#,*, Ling X, Wang J, Xiao Y, Shi S, Ji X, Shajii A, Gan ST, Kim NY, Duda DG, Xie T, Farokhzad OC, Shi J. Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition. Science Translational Medicine 2019, 11(523): eaaw1565. Highlighted: F1000Prime Recommendation - Rated Very Good

11. Ji X, Kang Y, Ouyang J, Chen Y, Zeng X, Xiao Y, Feng C, Qi B, Kim N, Saw P, Farokhzad OC, Tao W*. Synthesis of Ultrathin Biotite Nanosheets as an Intelligent Theranostic Platform for Combination Cancer Therapy. Advanced Science 2019, 6(19): 1901211. (Cover Paper; Web of Science Highly Cited Paper

10. Ouyang J, Feng C, Ji X, Li L, Gutti HK, Kim NY, Artzi D, Xie A, Kong N, Liu YN, Tearney GJ, Sui X, Tao W*, Farokhzad OC. 2D Monoelemental Germanene Quantum Dots: Synthesis as Robust Photothermal Agents for Photonic Cancer Nanomedicine. Angewandte Chemie International Edition 2019, 58(38): 13405-13410. 

9. Tao W*, Kong N, Ji X, Zhang Y, Sharma A, Ouyang J, Qi B, Wang J, Xie N, Kang C, Zhang H, Farokhzad OC, Kim JS. Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications. Chemical Society Reviews 2019, 48(11): 2891-2912. (Front Cover Paper; Web of Science Hot Paper | Highly Cited Paper 

8. Tao W*, Wang J, Parak W, Farokhzad OC, Shi J. Nanobuffering of pH-Responsive Polymers: A Known but Sometimes Overlooked Phenomenon and its Biological Applications. ACS Nano 2019, 13(5): 4876-4882. (Invited Article

7. Ling X, Tu J, Wang J, Shajii A, Kong N, Feng C, Zhang Y, Yu M, Xie T, Bharwani Z, Aljaeid BM, Shi B, Tao W*, Farokhzad OC. Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy. ACS Nano 2019, 13(1): 357-370. (Cover Paper; Web of Science Highly Cited Paper

6. Islam MA#, Xu Y#, Tao W# (equal contribution), Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J. Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nature Biomedical Engineering 2018, 2(11): 850-864. (Highlighted in the "Delivery of drugs and biologics" Collection from Nature Biomedical Engineering)

5. Tao W, Ji X, Zhu X, Li L, Wang J, Zhang Y, Saw PE, Li W, Kong N, Islam MA, Gan T, Zeng X, Zhang H, Mahmoudi M, Tearney GJ, Farokhzad OC. Two-Dimensional Antimonene-based Photonic Nanomedicine for Cancer Theranostics. Advanced Materials 2018, 30(38): 1802061. (Cover Paper; Web of Science Highly Cited Paper

4. Rosenblum D#, Joshi N#, Tao W# (equal contribution), Karp JM, Peer D. Progress and challenges towards targeted delivery of cancer therapeutics. Nature Communications 2018, 9(1): 1410. (Web of Science Hot Paper | Highly Cited Paper)

3. Zhu X, Ji X, Kong N, Chen Y, Mahmoudi M, Xu X, Ding L, Tao W*, Cai T, Li Y, Gan T, Barrett A, Bharwani Z, Chen H, Farokhzad OC. Intracellular Mechanistic Understanding of 2D MoS2 Nanosheets for Anti-Exocytosis Enhanced Synergistic Cancer Therapy. ACS Nano 2018, 12(3): 2922–2938. (Web of Science Highly Cited Paper

2. Tao W, Ji X, Xu X, Ariful IM, Li Z, Chen S, Saw PE, Zhang H, Bharwani Z, Guo Z, Shi J, Farokhzad OC. Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy. Angewandte Chemie International Edition 2017, 56(39): 11896-11900. (Cover Paper; Web of Science Highly Cited Paper

1. Tao W, Zhu X, Yu X, Zeng X, Xiao Q, Zhang X, Wang X, Ji X, Shi J, Zhang H, Mei L. Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics. Advanced Materials 2017, 29(1): 1603276. (Cover Paper; Web of Science Hot Paper | Highly Cited Paper