Presentations

What is the Value of Better Research? How Research Methods Affect Conclusions and Impact, at Harvard Business School, Ec3118 - Seminar in Economics of Science and Engineering, Baker 102., Friday, April 26, 2019

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Can Big Biomedical Research Data Help Increase Value and Reduce Waste?, at Harvard-MIT Center for Regulatory Science, Monday, February 4, 2019

Inadequate Methods and Poor Reporting in Biomedical Research, at International Network on the Value of Health Research, National Bureau of Economic Research, Friday, September 14, 2018

What is the Role of Public and Private Funding Sources in Science?, at International Network on the Value of Health Research, National Bureau of Economic Research, Friday, September 14, 2018

Joint work with Matthew Grennan and Kyle Myers

Quality and Bias in Biomedical Research, at The Value of Medical Research Pre-Doctoral Meeting, National Bureau of Economic Research, Friday, June 8, 2018

Two Hundred Years of Medical Care and Health, at Cohort Studies Meeting, National Bureau of Economic Research, Friday, May 11, 2018

Joint work with David Cutler and Thomas Getzen

Factors Associated with Quality and Bias in Biomedical Research, at Harvard PhD in Health Policy Research Seminar, Department of Health Care Policy, Harvard Medical School, Tuesday, April 17, 2018

Knowledge Synthesis: From Medical Research to Medical Practice, at Department of Medicine, NYU School of Medicine, Wednesday, April 4, 2018

The Buyer's Curse, at CEAR/MRIC Behavioral Insurance Workshop 2017, Georgia State University, Atlanta, Thursday, December 7, 2017

Joint work with Richard Zeckhauser

Improving Target Efficiency in Disease Management Programs, at Harvard PhD in Health Policy Research Seminar, Department of Health Care Policy, Harvard Medical School, Tuesday, February 14, 2017

Joint work with Tim Simcoe and Paul Gertler

Recent Publications

Maryaline Catillon. Working Paper. “Medical Knowledge Synthesis: A Brief Overview, 2017”. NBER white paper Abstract

The value of medical research derives from its ability to impact further research and medical practice. Medical knowledge synthesis, bridging the gap between current research, future research and medical practice, is a rapidly changing industry. The expanding mass of medical information makes knowledge synthesis evermore essential to enable and inform evidence-based decision-making. Systematic reviews (SRs), clinical practice guidelines (CPGs), textbooks and electronic information tools are the dominant modes of medical knowledge synthesis.

Over the last fifty years, the number of systematic reviews and guidelines has increased more rapidly than the publication of new original research. High standards have been developed for SRs and CPGs, but they are not widely adopted. Some medical research questions are over-covered by multiple and sometimes contradictory systematic reviews and guidelines, while others questions are not covered at all by high-quality knowledge synthesis. Until recently, textbooks were, with colleagues, the main source of information for clinicians. They have been supplanted by the Internet and point-of-care resources. The integration of high quality and up-to-date evidence varies across textbooks and electronic information tools.

This white paper summarizes important and practical information on Systematic Reviews (SRs), Clinical Practice Guidelines (CPGs), medical textbooks and point-ofcare resources, discusses their interrelationship and evolution, and the evidence on their quality, use and impact on medical practice.

Maryaline Catillon, David Cutler, and Thomas Getzen. Working Paper. “Two Hundred Years of Health and Medical Care: The Importance of Medical Care for Life Expectancy Gains”. NBER working paper Abstract

Using two hundred years of national and Massachusetts data on medical care and health, we examine how central medical care is to life expectancy gains. While common theories about medical care cost growth stress growing demand, our analysis highlights the importance of supply side factors, including the major public investments in research, workforce training and hospital construction that fueled a surge in spending over the 1955-1975 span. There is a stronger case that personal medicine affected health in the second half of the twentieth century than in the preceding 150 years. Finally, we consider whether medical care productivity decreases over time, and find that spending increased faster than life expectancy, although the ratio stabilized in the past two decades.

Maryaline Catillon. 9/3/2019. “Trends and Predictors of Biomedical Research Quality, 1990-2015: A Meta-Research Study.” BMJ Open. Publisher's Version

Maryaline Catillon, Ph.D.

Research Associate

Presentations

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Recent Publications